Abstract

A reconfigurable transistor glucose biosensor was fabricated using the BESOI MOSFET structure. Glucose oxidase enzyme was immobilized on the sensitive regions of the device to specifically detect glucose. The experimental measurements showed a positive linear relationship between the sensitivity and the glucose solution concentration, in the measured range (0–200 mM). The maximum value of 0.52 was obtained for programming gate voltage VGB = 15 V. Next, numerical simulations based on the previous experimental results enabled the study of the channel thickness influence on the sensitivity. An optimal channel thickness value of 10 nm was obtained, in which the generated charges due to the glucose oxidation reaction most impact the drain current level of this device.

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