Abstract
Abstract The aminocyclitol moiety of fortimicin A, (−)-fortamine, was synthesized in an enantioselective manner starting from the chiral half ester, easily available by the enantioselective hydrolysis of a symmetrical diester with pig liver esterase. The present approach provides a general and efficient route to variously substituted 1,4-diaminocyclitol-derivatives.
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