Abstract
This study examined the effects of specific psychosocial factors on the progression of HIV infection in 200 HIV-1 seropositive but asymptomatic men and women. At baseline, participants' disease status was determined, and they were administered self-report assessments of coping style, social support and loneliness. Participants were classified at 6 and 12 month follow-ups as progressed or unchanged, compared to their baseline status. In logistic regression analyses, higher baseline Type C coping scores (indicating emotional inexpressiveness and decreased recognition of needs and feelings) significantly predicted progression at 6 months ( p <0.01) and 12 months ( p <0.02), but only among participants classified at baseline as CDC-A2 (between 200-499 CD4 cells/mm 3 ). In participants originally classified as CDC-A1 (CD4 cell counts > 500/mm 3 ), no psychosocial variable showed any significant relationship. Results emphasize the need to consider the disease context, as well as the interaction between biological and psychological factors in contributing to disease progression.
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