Abstract

The present study represents the thermodynamic interactions between the non-ionic surfactant Tween 20 and the well-known flavonoid quercetin. The conductivity experiments were conducted at five different temperatures (20 °C, 25 °C, 30 °C, 35 °C and 40 °C) using various quercetin concentrations (1 mM, 2 mM and 3 mM) in 70 % v/v ethanol as a solvent. To overcome the non-conducting behavior of non-ionic surfactant Tween 20, as an electrolyte, sodium chloride solution (1 % w/v) was added. The critical micelle concentration (CMC) and XCMC values were calculated as a function of temperature using the specific conductivity experiments. In addition, a number of thermodynamic parameters, including change in Gibbs free energy of micellization (ΔGom), change in enthalpy (ΔHom), and entropy (ΔSom), have been estimated. Overall, the effects of quercetin on Tween 20′s micellization behaviour have been studied.

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