An electrical stimulation on retinal ganglion cell for retinal prosthesis based on CMOS image sensor: A study of electrophysiological simulation

Abstract

Establishing a visual perception for patient who bear a disability on the retinal cells, a strategy of acquisition the external image information from an image sensor and transmitting of its information to implanted electrodes have studied in many papers. Although a construction of a CMOS (complementary metal oxide semiconductor) image sensor as an image acquisition device has been improved, the images taking from an image sensor still include several noises (e.g. thermal noise, random noise, dark current). Moreover, noise can be generated on the occasion of data transmission from an image sensor to electrodes. In this study, we proposed a fundamental method and a condition for functional electrical stimulation on the retinal ganglion cell based on the CMOS image sensor with higher frame rate, and we studied the influence of noise element on the reaction of retinal ganglion cell.