Abstract

The synthesis of novel polycyclic thiopyrano coumarin/chromone frameworks through intramolecular domino Knoevenagel hetero Diels–Alder reactions of 4-hydroxy coumarin and its benzo-analogous with S-prenylated aromatic aldehydes was studied. A high degree of chemoselectivity was achieved by the application of microwave irradiation and a solid support.

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