An Efficient Synthesis of Spirocyclopropanes by [2+1] Annulation of α,β‐Unsaturated Carbonyl Compounds with Nitroacetates

Abstract

AbstractAn efficient synthesis of spirocyclopropanes was developed via [2+1] annulation of α,β‐unsaturated carbonyl compounds with nitroacetates. This protocol features advantages such as simple operation, broad substrate scope, high diastereoselectivity and good to excellent yields. Moreover, this work represents the first example of assembling spirocyclopropane derivatives from nitroacetates.