Abstract

The title compound 1 is prepared from ε-caprolactam in a five-step sequence involving N-alkylation of the azepine ring from a 3-(phenylselanyl)-3-(benzyloxycarbonyl) derivative 4 and the generation of the 3-carboxyazepine moiety from the resulting diester 5 by ozonolysis followed by catalytic hydrogenation.

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