Abstract

A convenient route to enantiopure azetidine-2,3-diones is described. The chiral ketene generated from commercially available l-(+)-diethyl tartrate on Staudinger cycloaddition with different imines gave spiro-β-lactams in good yields. These spiro-β-lactams were transformed into azetidine-2,3-diones in excellent yields in a two-step process.

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