Abstract
A convenient route to enantiopure azetidine-2,3-diones is described. The chiral ketene generated from commercially available l-(+)-diethyl tartrate on Staudinger cycloaddition with different imines gave spiro-β-lactams in good yields. These spiro-β-lactams were transformed into azetidine-2,3-diones in excellent yields in a two-step process.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have