Abstract
Rattle-type Fe3O4@SiO2 hollow mesoporous spheres with large cavities have been successfully prepared by using the colloidal carbon spheres as the templates. The spheres are well monodisperse and nearly uniform in dimension with particle size of ca. 900 nm. The thickness of the mesoporous silica shell is about 100 nm, and only one Fe3O4 particle of ca. 100 nm in diameter is encapsulated in each hollow mesoporous silica sphere. The magnetic measurement indicated that the Fe3O4@SiO2 hollow mesoporous spheres exhibited ferromagnetic behavior with the magnetization saturation of 1.6 emu/g. Using aspirin as a model drug, the Fe3O4@SiO2 hollow mesoporous spheres showed high drug loading capacity and sustained release property. Therefore, this kind of magnetic hollow mesoporous spheres provides a very promising candidate for application in a targeted drug delivery system.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
