An Efficient Probe of Cyclometallated Phosphorescent Iridium Complex for Selective Detection of Cyanide.

Abstract

A cyclometallated phosphorescent iridium-based probe to detect CN– was prepared through a cyanide alcoholize reaction based on the C^N type main ligand and N^N type ancillary ligand (2-phenyl pyridine and 1,10-phenanthroline-5-carboxaldehyde, respectively). The efficient probe exhibited good sensitivity in response to CN– in an CH3CN and H2O (95/5) mixture within a 1.23 μM detection limit. The response of PL is directly in line with the concentration of CN– from 0 to 2.0 equiv. The PL investigation of other reactive anions proved the great selectivity to CN–. Additionally, upon adding 1.0 equiv. of cyanide, the formation of cyanohydrin was correctly elucidated in 1H NMR, FT-IR, and mass spectra studies. The conspicuous results indicate that the iridium complex has the potential possibility of application in other biosystems related to CN–.