An Efficient One-Pot Synthesis of Novel Fused Pyrroles and Indoles by Dipolar Cycloaddition under Microwave and Conventional Conditions

Abstract

The straightforward synthesis of families of novel tri­cyclic and tetracyclic pyrrolino and indolino heterocycles in a one-pot [3+2]-cycloaddition reaction is described. The process enables the synthesis of diversified pyrroles or pyrrolines in high yields in a single step. Microwave and conventional thermal conditions were explored, with remarkable acceleration observed under the microwave conditions.