Abstract
AbstractA one‐pot tandem sequential protocol for efficient synthesis of a series of new pyranopyrazole derivatives has been developed involving Suzuki coupling of 4‐bromobenzaldehyde and arylboronic acids followed by a four‐component reaction from readily available ethyl acetoacetate, malononitrile, and hydrazine hydrate. All of the products were fully characterized by melting point, FTIR, 1H NMR, and 13C NMR spectroscopy, and HRMS. The structure of one of the products was further established by X‐ray diffraction analysis. This method should provide a useful strategy for the construction of pyranopyrazole heterocycles.
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