An Efficient and Tunable Route to Bis(1,2,3‐triazol‐1‐yl)methane‐Based Nitrogen Compounds

Abstract

AbstractA new and easy route to prepare “a la carte” bis(1,2,3‐triazol‐1‐yl)methane compounds, namely bmtzm (1), bptzm (2), bttzm (3), bmtzpm (4), bptzpm (5), bttzpm (6), bmtzom (7), bptzom (8) and bttzom (9), with different functional groups is reported. The compounds were prepared by reaction between readily accessible alkynes and geminal diazides in a double Cu‐catalyzed azide‐alkyne cycloaddition (CuAAC) reaction. These materials were used as starting materials for the synthesis of more elaborate compounds. Thus, the preparation of new bis(1,2,3‐triazol‐1‐yl)methane‐based heteroscorpionate neutral precursors pbptztamH (10), pbttztamH (11), (S)‐mbptzamH (12) and (S)‐mbttzamH (13) and a dinuclear zinc complex, [Zn{pbptztam}Et]2 (14), was achieved. The structures of the compounds were determined by spectroscopic methods, and the X‐ray crystal structures of compounds 2, 3, 7, 8, 9 and 14 were established.