An efficient and rapid Mn(III) complex catalyzed synthesis of polyhydropyridine derivatives via Hantzsch 4 component condensation

Abstract

A facile and an efficient one-pot synthesis of polyhydroquinoline derivatives in high yields using N,N′-bis (benzoylacetone) ethylenediamine manganese (III) chloride as an environmentally friendly mild Lewis acid catalyst with high catalytic activity and reusability via the Hantzsch reaction in short reaction time was reported. The reaction proceeded to completion within 5–25min in 90–97% yield. All of the obtained compounds were obtained in high purity without any use of more purification and characterized by physical and spectroscopic data.