Abstract
Abstract A one-pot three-component condensation of aromatic aldehyde, aromatic ketone, and malononitrile leading to an efficient synthesis of 2-amino-4,6-diarylbenzene-1,3-dicarbonitrile and 1,2-dihydro-2-oxo-4,6-diarylpyridine-3-carbonitrile has been carried out in a mortar just by grinding or heating under solvent-free conditions. Compared with the classical reaction conditions, these new synthetic methods have the advantages of excellent yields, shorter reaction time, and mild reaction conditions.
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