An Effective of Ensemble Boosting Learning Method for Breast Cancer Virtual Screening Using Neural Network Model

Abstract

Radial Based Function Neural Network models (RBFNN) are currently used deep-rooted methods for assessing the stages of diagnosis of chronic diseases. The goals of this research are to suggest a model for the diagnosis of breast cancer, and to be able to estimate the stages of development of pre-malignant breast tumors. The significance of the study is to develop an integrated RBF neural network with ensemble features using the boosting method. The importance of the ensemble boosting method is to generate a sequence of models to achieve more precise predictions. One of the ensemble boosting advantages is that it can take longer to build and to score than a RBF NN standard model. By using ensemble boosting, the accuracy of breast tumor diagnosis increased and thus it became easier to know the stage of the tumor, and whether it was malignant or benign. This will help doctors to select appropriate treatment for each tumor stage, consequently leading to the salvage of cancer patients with this type of tumor. The suggested RBFNN method was examined on the different type of UCI breast cancer datasets. The general diagnosis accuracy based on 10-fold cross validation using RBFNN method obtained 97.4%, 98.4%, 97.7% and 97.0% for the WBC, BCD, BCP, and WBCD UCI datasets respectively. The effectiveness of the proposed method was confirmed by comparing accuracy improvement both before and after using ensemble boosting, and it was found to be more accurate compared with other breast cancer diagnosis methods such as Logistic Regression (91.5%), KNN (96%), SVM (89%), Decision tree (95.13), CNN (97.66%), and Naive Bayes (91%).