Abstract
The effect of dietary sulfur on liver inorganic sulfate concentration was determined by feeding rats diets containing 0.0002, 0.02, 0.1 and 0.42% of inorganic sulfate for a period of 17 days. Each diet contained 15% of casein supplemented with decreasing levels of methionine as the dietary inorganic sulfate was increased, to keep the sulfur as sulfate concentration constant at 0.67%. The molarity of the liver sulfate calculated on the basis of moles of sulfate per 1,000 g of wet tissue was 0.98, 1.3, 2.2 and 1.5 mM for rats fed the diets containing 0.0002, 0.02, 0.1 and 0.42% of inorganic sulfate, respectively. Thus it appears that the liver sulfate pool is limited by a combination of the rate of oxidation of the sulfur-containing amino acids and the extraction of sulfate from the portal system.
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