Abstract
In this mini-review we will refer to some very modern perspectives regarding the latest developments regarding the relevance of Xenobots in the biomedical research. In this way, Xenobots are a real scientific enigma, halfway between frog and robot, and they're totally changing the way we think about life and machines. They're like a living, crawling puzzle that scientists are still trying to solve. Thus, we will try to cover aspects by mentioning the Half-frog, Half-robot status of the Xenobots, some ethical issues, their place in the nature and some future perspectives in this area.
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