An Early Stage Researcher's Primer on Systems Medicine Terminology.

Stephen Todd,Karim Zouaoui Boudjeltia,Nissim Harel,Hui Wang,Harald Schmidt ,Massimiliano Zanin,Jose J. M. Sanchez-Bornot ,Arriel Benis,Su Yang,Ioan Ștefan Sacală ,Blaž Stres,Jan Baumbach,Ioanna Chouvarda,David D. H. Glass ,Tijana Šušteršič ,Egils Stalidzāns ,George G. M. Spyrou ,David D. P. Finn ,Tomas Iešmantas ,Ioannis Symeonidis,Estelle Pujos‐Guillot ,Magda Bucholc,Haiying Wang,Chandan C. K. Behera ,Damjana Rozman,Girijesh Prasad,Dahui Wang ,Liam L. P. Maguire ,Jordi Solé-Casals,José Basílio ,Milena Veneva,Johannes A. Schmid,Francesco Pappalardo,Niamh McCombe,Trevor Sharp,Tien Tuan Dao ,Steven Watterson,Alok Joshi,Filippo Castiglione,Ilinka Ivanoska,Blandine Comte,Nadim N. A. A. Aitya ,Vojtěch Spiwok,Mihnea Alexandru Moisescu,Kristel Van Steen,Kongfatt Wong‐Lin ,Badr Kaoui,Daman Kaur,Nenad Filipović ,Paolo Tieri,Xuemei Ding,Paula P. L. Mcclean ,Annikka Polster,Xin Zou,J. M. Miranda

doi:10.1089/nsm.2020.0003

Abstract

Background: Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an environment. Exploring Systems Medicine implies understanding and combining concepts coming from diametral different fields, including medicine, biology, statistics, modeling and simulation, and data science. Such heterogeneity leads to semantic issues, which may slow down implementation and fruitful interaction between these highly diverse fields.Methods: In this review, we collect and explain more than100 terms related to Systems Medicine. These include both modeling and data science terms and basic systems medicine terms, along with some synthetic definitions, examples of applications, and lists of relevant references.Results: This glossary aims at being a first aid kit for the Systems Medicine researcher facing an unfamiliar term, where he/she can get a first understanding of them, and, more importantly, examples and references for digging into the topic.

Highlights

Death has always been the end of every human’s life, mankind has been trying to delay that as much as possible
Background: Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an environment
Such heterogeneity leads to semantic issues, which may slow down implementation and fruitful interaction between these highly diverse fields

Summary

Medicine Terminology

Massimiliano Zanin,1,* Nadim A.A. Aitya,[2] Jose Basilio,[3] Jan Baumbach,[4] Arriel Benis,[5] Chandan K. Behera,[2] Magda Bucholc,[2] Filippo Castiglione,[6] Ioanna Chouvarda,[7] Blandine Comte,[8] Tien-Tuan Dao,[9,10] Xuemei Ding,[2] Estelle Pujos-Guillot,[8] Nenad Filipovic,[11,12,13] David P. McClean,[20] Niamh McCombe,[2] Joao Luıs de Miranda,[21,22] Mihnea Alexandru Moisescu,[23] Francesco Pappalardo,[24] Annikka Polster,[25] Girijesh Prasad,[2] Damjana Rozman,[26] Ioan Sacala,[23] Jose M.

Introduction

Complex networks

Decision support systems

Deep learning

Digital Health

If p

Graph embedding

Network Analysis Software