Abstract

It has been shown that compared with metformin monotherapy, an early combination treatment of saxagliptin and metformin significantly improves glycemic control with no increase in adverse effects in type 2 diabetic patients. The efficacy and safety profiles of saxagliptin/metformin fixed dose combination products are similar to those of the two-drug combination therapy, with lower frequency of administration and better compliance. Therefore, we believe that this drug will bring benefits to more type 2 diabetic patients in China. (Chin J Endocrinol Metab, 2016, 32: 346-348) Key words: Diabetes mellitus, type 2; Metformin; Saxagliptin; Fixed dose combination

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