Abstract

A 49‐year‐old Japanese woman, who developed adrenal and thyroid insufficiency approximately 8 years prior to death and expired from adrenal insufficiency was described. No specific endocrinological and immunological tests were performed. Autopsy revealed idiopathic Addison's disease, Hashimoto's thyroiditis, acute glomerulonephritis and primary hyperplasia of parathyroid gland. Reviewing the literature some comments were made on the incidence, morphology and pathogenesis of idiopathic Addison's disease and Schmidt's syndrome. This is the first case of Schmidt's syndrome as well as of idiopathic Addison's disease in Japan. ACTA PATH. JAP. 20: 215 ‐ 226, 1970.

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