Abstract
A case of cryptococcal meningitis of a 32-year-old Japanese female was reported. The diagnosis of this case was determined only by histological examination after autopsy.She died about a half year after se complained of headache as initial symptom.1). Pathologically. A grayish, gelatinous, small nodule irregural in shape was found at the subpleural part of the right upper lung. There was thickening an i opacity with a bloody appearance of the meninges over the basal and occipital surface.2). Microscopically. In the lung a granulomatous lesion was disclosed being composed of lymphocytes, mononuclears, multinucleated giant cells with dense fibrosis. There was no leucocytic element. Numerous cryptococci were presented in the necrotized center of this lesion.3) From the histopathological findings, it would appear that death resulted from cryptococca meningitis spreading from primary focus in the lung.
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