Abstract
Background: A rising number of patients with non–valvular atrial fibrillation are now treated with a novel oral anticoagulant (NOAC) rather than warfarin. Novel oral anticoagulants require dose-adjustment based on a number of factors including age, absolute creatinine level, and calculated creatinine clearance. Overdosing and underdosing of NOACs is common and is associated with adverse patient outcomes.
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