An atypical case of multifocal infantile haemangioma in a child after Highly Active Antiretroviral Therapy (HAART) during pregnancy

Abstract

Haemangioma is a benign congenital vascular neoplasm, which ost commonly affects the skin [1]. It is the most common tumour f infancy, affecting approximately 10% of children under 1 year of ge. The use of HAART in pregnancy along with caesarean section nd formula feeding, has reduced the rate of vertical transmission f HIV from about 25% to 1–2%. However, it has been suggested that ntiretroviral drugs may have teratogenic effects [2] and may play role in the pathogenesis of haemangiomas [3]. We report here an atypical case of periorbital haemangioma ith response to corticosteroids, but persistent intracranial lesions onsistent with haemangioma and developmental cysts, in a AART exposed Caucasian Italian child, born to an HIV positive other.