Abstract
An antibody raised against dynorphin 1–8 was immunoreactive in the rat neurohypophysis in vasopressin but not in oxytocin endings. Oxytocin but not vasopressin terminals were immunostained when a Met5-enkephalin, a N-terminally directed monoclonal β-endorphin antibody and an enkephalin-Met5-Arg6-Phe7 antibody were applied. The immunocytochemical reactions indicate that oxytoxin terminals and their granules store pro-enkephalin-A derived opioid peptide fragments.
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