Abstract
Requirement of artificial bone materials is high, which demands us to consider many factors of human body. Evidence exists that estrogen influences neuronal physiology and cognitive function. Bone mineral density has been proposed as a marker for cumulative estrogen exposure. This study examined whether choice reaction time (CRT) would be related to calcaneus quantitative ultrasound (QUS). 222 ethnic Han Chinese men were recruited. Besides age and body mass index (BMI), cigarette smoking, as an important environment factor influencing cognition and bone health, was included in covariants. Results showed that CRT performance was statistically significantly positively correlated with bone quality index (p < 0.01) and speed of sound (SOS) (p < 0.001) before controlling covariants. After adjustment for age, BMI, and smoking, CRT remained significantly related to SOS (p < 0.05). Our findings indicate that CRT may be associated with bone status, which suggests an effect of artificial bone on nervous system should be considered when it is produced.
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