Abstract
An artificial plastic receptor that can discriminate axial asymmetry of optically active binaphthyldiamine derivatives was prepared by the ‘molecular imprinting’ technique. A light-radical polymerization in the presence of an axially asymmetric compound, ( R)-2,2′-bis-methylcarbonylamino-1,1′-binaphthyl (binaphthyldiamine bis-acetamide (BINADA-ac)) as a template molecule with methacrylic acid (MA) as a functional monomer, and ethyleneglycol dimethacrylate (EGDMA) as a crosslinker, at 4°C. The obtained polymer exhibited a superior enantioselectivity to the ( R)-enantiomer by HPLC analyses. This plastic receptor should recognize the template molecule with its shape and character of its functional groups. It should be useful in the development of chiral stationary phases for the optical resolutions of axially asymmetric compounds.
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