Abstract

Low-resolution and ill-posedness are the major challenges in diffuse optical tomography(DOT)/fluorescence molecular tomography(FMT). Recently, the multi-modality imaging technology that combines micro-computed tomography (micro-CT) with DOT/FMT is developed to improve resolution and ill-posedness. To take advantage of the fine priori anatomical maps obtained from micro-CT, we present an arbitrary boundary triangle mesh generation method for FMT/DOT/micro-CT multi-modality imaging. A planar straight line graph (PSLG) based on the image of micro-CT is obtained by an adaptive boundary sampling algorithm. The subregions of mesh are accurately matched with anatomical structures by a two-step solution, firstly, the triangles and nodes during mesh refinement are labeled respectively, and then a revising algorithm is used to modifying meshes of each subregion. The triangle meshes based on a regular model and a micro-CT image are generated respectively. The results show that the subregions of triangle meshes can match with anatomical structures accurately and triangle meshes have good quality. This provides an arbitrary boundaries triangle mesh generation method with the ability to incorporate the fine priori anatomical information into DOT/FMT reconstructions.

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