An Approach to P=N Bond Formation: Straightforward Synthesis of Arylurea‐Derived Phosphazenes via Condensation of Ph3P=O with N‐Monosubstituted Arylureas

Abstract

AbstractThe Hendrickson's reagent‐mediated formation of the P=N bond provides access to arylurea‐derived phosphazenes compounds using readily available N‐monosubstituted arylureas and Ph3P=O. Various functional groups were tolerated to give arylurea‐derived phosphazenes in the yield of 71–93%. The reaction also provides an alternative strategy for constructing compounds containing P=N bond. In this transformation, the Hendrickson's reagent unprecedented selectively reacts with the free amine group instead of the oxygen atom of N‐monosubstituted arylurea. In addition, we found that thioureas could act as an effective thionating agent by converting Ph3P=O to Ph3P=S.