Abstract
A number of amines have been alkylated at the position alpha to nitrogen via free radical methodology. N-(2-Iodobenzyl) and N-(2-iodobenzoyl)‘protected’ amines have been used to generate radicals which rapidly undergo a 1,5-hydrogen shift to give more stable α-amino radicals. These can subsequently be trapped by electron deficient alkenes to give α-alkylated amines.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
