Abstract
BackgroundHolothuria scabra is the potential source of terpene with high antioxidant capacity and one of the most valuable species in the trade.ResultsThe results indicated that antioxidant activity of crude methanol extracts and three pure compounds, Friedelin, 3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde, from sea cucumber was determined using DPPH, Folin–Cioccalteau reagent. The results indicated the total phenolic contents at 30.52.28 ± 0.21 GAE/g dry weight equivalent and the effective concentration (EC50) value were found to be 33.77 ± 0.24, 14.63 ± 0.01, 14.62 ± 0.01 and 14.78 ± 0.11 mg/ml whole body of Holothuria scabra, Friedelin, 3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde, respectively.ConclusionIn conclusion, the methanol extract and pure compounds of whole body parts of sea cucumber showed the highest antioxidant activity with EC50 value of 33.77 ± 0.24, 14.63 ± 0.01, 14.62 ± 0.01 and 14.68 ± 0.11 mg/ml. It also showed the highest total phenolic content at 30.52 ± 0.21 GAE/g dry weight.Graphical abstractHolothuria scabra is the potential source of terpene with high antioxidant capacity. In this study, antioxidants activity of crude methanol extracts and three pure compounds, Friedelin, 3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde, from sea cucumber was determined using DPPH, Folin−Cioccalteau reagent. The results indicated the total phenolic contents and the effective concentration (EC50) value
Highlights
Holothuria scabra is the potential source of terpene with high antioxidant capacity and one of the most valuable species in the trade
We focused on H. scabra, commonly known as sandfish, and one of the most valuable species in the trade [14], is a marine invertebrate in the family Holothuriidae
The percent yield of extract obtained from 50 g of dry material was measured for each extract
Summary
Holothuria scabra is the potential source of terpene with high antioxidant capacity and one of the most valuable species in the trade. Free radicals are highly active atoms or molecules with unpaired valence electron [1] They play an important role in human body, such as involvement in the energy creating process, the cell growth, the signalling process and immunization process [2]. Owing to their high activity, they can cause various cell and tissue disorders as well as destruction or modification of DNA structure [3]. Terpenes are large and diverse class of organic compounds, produced by a variety of plants, microbes and animals It comprises a high variety of more than 100,000 different structures [5] which can be divided into several sub-groups, such as monoterpenes, sesquiterpenes, diterpenes and triterpenes.
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