An Analysis on the Drug Using Rules of Radix Paeoniae Alba in Fuqingzhu Medicine for Women

Abstract

Objective: Systematizing the internal consumption prescriptions containing radix paeoniae alba in Fuqingzhu Medicine for Women - Women's Volume, exploring the rules of Fu Qingzhu's use of radix paeoniae alba and her academic thoughts. Methodology: Fuqingzhu Medicine for Women, published by China Medical Science Press in January 2019, was used as a search source for extracting and organizing the prescriptions that met the inclusion criteria, establishing a database, and analyzing the frequency, preparation method and dose of the medicines and prescriptions. Meanwhile, the association rules of high-frequency drugs were analyzed separately with the help of SPSS modeler software. Results: In the end, 33 prescriptions were included, and it was found that radix angelicae sinensis, atractylodes macrocephala and prepared rehmannia root were more frequently paired with radix paeoniae alba. The association rules showed that five core drug groups were obtained, namely radix paeoniae alba-radix angelicae sinensis, radix paeoniae alba-atractylodes macrocephala, radix paeoniae alba-prepared rehmannia root, radix paeoniae alba-ginseng, radix paeoniae alba-glycyrrhiza glabra, etc. The drug combinations were mainly blood and Qi tonics. For the preparation of radix paeoniae alba, stir-frying with wine is the main technique; the average dosage of radix paeoniae alba is 8.21 qian(equivalent to 30.63 g nowadays), and the large dosage of radix paeoniae alba is mainly used to treat various gynecological diseases caused by liver stagnation and its failure to store blood. Conclusion: For the treatment of gynecological diseases, Fu Qingzhu used radix paeoniae alba mostly, which is a pure and mild medicine(without any harsh product). This medication will regulate the liver and spleen thus adjusting the Qi and blood for the harmonization of the conception and governor vessels, fully reflecting the academic thought that "the liver is the precondition for women" and "the spleen is the source of qi and blood".