Abstract
BackgroundThe aim of the present investigation was to evaluate the literature recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants. It’s important to know the characteristics present in these lesions and possible effects on the prognosis of dental implants.MethodsAn electronic search without time restrictions was done in the databases: PubMed/Medline. With the keywords "Granuloma" OR "Granuloma, Giant Cell" OR "peripheral giant cell" OR "Granuloma, Pyogenic” AND "Dental implants" OR "Oral implants”.ResultsAfter applying the inclusion and exclusion criteria, a total of 20 articles were included, which reported 32 lesions (10 pyogenic granulomas, 21 peripheral giant cell granulomas and one peripheral giant cell granuloma combined with peripheral ossifying fibroma, all associated with implants). According to our review, these lesions are more frequent in males and in the posterior region of the mandible. Both excision and curettage of the lesion, compared to only excision, presented similar recurrences (40%). Explantation of the implant was performed in 41% of cases without additional recurrences. The results are not statistically significant when comparing one lesion to the other in terms of explantation (p = 0.97), recurrence (p = 0.57) or bone loss (p = 0.67).ConclusionsThe main therapeutic approach is tissue excision. The lesions show a high recurrence rate (34.4%), which often requires explantation of the associated implant. This recurrence rate is not affected by curettage after excision.
Highlights
The aim of the present investigation was to evaluate the literature recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants
The aim of the present study was to search the association of the available data published in the literature on pyogenic granuloma (PG) and Periapheral giant cell granuloma (PGCG) associated with dental implants, analyzing their recurrences, associated etiological factors and different treatment options
10 lesions were diagnosed as PG [9, 22, 24,25,26, 28, 30, 31], 21 as PGCG [4, 9, 11, 17, 19,20,21, 23, 29, 32,33,34] and one combined PGCG with an ossifying peripheral fibroma [24]
Summary
The aim of the present investigation was to evaluate the literature recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants. Román‐Quesada et al BMC Oral Health (2021) 21:204 connective tissue in response to chronic irritation [9] Among these lesions, those most frequently observed in the oral cavity are pyogenic granuloma (PG), traumatic fibroma, fibroepithelial hyperplasia, peripheral ossifying fibroma and peripheral giant cell granuloma (periheral giant cell lesion, -PGCG-) [4, 9]. PG and PGCG are the reactive lesions most frequently associated with teeth and implants [2, 9]. Some factors such as chronic inflammation, the accumulation of foreign bodies or corrosion of the implant surface could cause a chronic irritative process and act as contributing factors for mucositis and peri-implantitis and for PG and PGCG [3, 4, 10]
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