Abstract

The growth of crystals of glutamic dehydrogenase has been studied by electron microscopy and optical diffraction with the aim of elucidating why crystals large enough for X-ray structure determination have not been grown. Observation of individual crystals as well as small crystals in the process of growth indicate that before molecules are incorporated into the crystal, they form helical tubes and crystal growth is achieved mainly by association of the helical tubes, rather than single molecules. From earlier studies it is known that helical tubes of glutamic dehydrogenase are morphologically heterogenous and it is suggested that the association of different types of tubes into a single crystal may pose a limit to their ultimate size.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.