An analysis of clinical effect of loxoprofen sodium on alleviating the pain after uterine artery embolization

Abstract

Objective: To evaluate the clinical effect and feasibility of loxoprofen sodium in efficiently alleviating the pain after uterine artery embolization (UAE) pain. Methods: Twenty-four patients with uterine fibroids treated with UAE in our hospital between January and August in 2016 were selected for this study. They were randomly divided into observation group (n=12) and control group (n=12). The observation group were treated with loxoprofen sodium 60 mg/time and 3 times/day while control group received an oral administration of loxoprofen sodium 60 mg / ?. The visual analogue scale (VAS) of the two groups at different time (0,4,8,16,24,48 h) was compared to evaluate the degree of the pain. The comfort degree was evaluated by Brinell comfort score (BCS). Results: The VAS scores of the observation group were significantly lower than those of the control group at 0, 4, 8, 16, 24 and 48 h after operation (P <0.01). The BCS scores of 0,4,8,16,24,48 h of the observation group were significantly higher than those of the control group (P <0.05). Conclusions: The loxoprofen sodium can greatly reduce the degree of postoperative pain of UAE and improve the comfort and satisfaction of patients, thus, it is worth of clinical application. Key words: Loxoprofen sodium; Preemptive analgesia; Uterine artery embolization; Pain