Abstract
See and treat: An amphiphilic bisporphyrin and its YbIII complex Yb⋅1 are characterized by an appropriate hydrophobicity/hydrophilicity balance for membrane transport. Their cellular uptake by a rat tumor-cell model is ten times higher than that of the parent tetracationic porphyrin, and their activity as photodynamic therapeutics is correspondingly stronger. The near-IR-luminescence of Yb⋅1 is potentially useful for tumor imaging. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2268/2008/z700767_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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