Abstract
Objective:To compare the pre-procedural anxiety and depression levels of patients undergoing chorion villus sampling (CVS) and amniocentesis (AC).Methods:Patients referred to our department for fetal karyotype analysis with a positive first or second trimester screening test for aneuploidy between January 2013 to June 2015 were included. CVS and AC procedures were performed in patients with gestation periods of between 11-14 and 16-20 weeks, respectively. Anxiety was evaluated using the Spielberger State-Trait Anxiety Inventory (STAI), and depression was assessed using the Beck Depression Inventory II (BDI-II).Results:A total of 1,400 patients were included. Compared to first trimester controls, patients undergoing CVS had significantly higher STAI-state and BDI-II results. Likewise, patients undergoing AC had higher STAI-state and BDI-II scores than controls in the second trimester. In terms of STAI-trait results, no difference was found between the groups. Our results also showed that, compared to AC group, patients undergoing CVS had similar STAI-state, STAI-trait and but higher BDI-II scores.Conclusion:We conclude that evaluating the stress and depression levels of these patients should be one of the routine procedures in pregnancy follow-up.
Highlights
Pregnancy itself is one of the most stressful and depressing periods in a woman’slife.[1]
The earliest procedure is chorion villus sampling (CVS), which is typically performed at a gestation period of between 10 and 14 weeks
The protocol of this study was approved by the ethics committee for human studies at our university, and informed consent was obtained from all participants before the study was conducted between January 2012 and June 2015
Summary
Pregnancy itself is one of the most stressful and depressing periods in a woman’slife.[1] The possibility of miscarriage or other perinatal problems is the main cause of this condition. Prenatal diagnosis of fetal abnormalities, fetal aneuploidies, are of major interest to contemporary perinatal medicine. It is clear that all approaches, including invasive methods, are usually used for confirming the precise diagnosis of an abnormality. The procedures used for fetal genetic analysis are divided according to the gestational time and the indicated tissues.[2,3] The earliest procedure is chorion villus sampling (CVS), which is typically performed at a gestation period of between 10 and 14 weeks
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