An alarming public health concern over variability in herbal compositions of marketed immunity booster products during COVID-19: A botanical survey-based study

Abstract

The world is going through pandemic of the century named COVID-19 disease. The COVID-19 pathogenesis involves cytokine storm in advanced stage leading to systemic hyper-inflammation. Medicinal herbs are practiced as part of alternative therapies in addition to clinically approved drugs with strong belief of its safety and efficacy. In present times, many herbal immunity booster products are available in market which claims to boost immunity for fighting against COVID-19 in prevention and cure. In this study, herbal products with tag of Immunity boosters were surveyed from medical stores and studied for their botanical contents. We surveyed 60 herbal products out of which 31% were tablets and rest were other forms like capsule, decoction and avaleha. Among the products, 17% products were from Dabur followed by Himalaya, Zandu and rest other leading brands of herbal market. Total 98 plants belonging to 50 diverse plant families like Zingiberaceae, Lamiaceae, Piperaceae and Apiaceae were reported being used in these products. Including Fruits (19%), Root (18%) and Leaf (17%), total 20 different plant parts were found used as medicinal herbs. These herbal products were having 10.27 ± 14.02 herbs with range of 56 indicates huge ingredient variation among the products. This diversity in products poses serious health concern in buyers who do not know the safety and efficacy of immunity boosters, being used in COVID-19 pandemic.