Abstract
Cell cultures of the Aedes aegypti (Peleg) cell line contain an agent that causes marked syncytium formation of Aedes albopictus cells. A plaque assay was used to measure the growth of the cell fusing agent (CFA) in A. albopictus cultures, and it was found to have a latent period of about 12 hr. It failed to replicate in or cause fusion of BHK, KB or Vero cells. The CFA was sensitive to ether and to deoxycholate and sedimented in a sucrose velocity gradient more slowly than did Sindbis virus. The preliminary evidence suggests that the CFA may be similar to the group B togaviruses.
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