Abstract
Tropomodulin family of proteins includes several isoforms of tropomodulins (Tmod) and leiomodins (Lmod), which are differentially expressed in various tissues. They bind to the pointed end of an actin filament and regulate dynamics at that end. By binding to G-actin they sequester actin or nucleate actin polymerization. Of Tmod isoforms, Tmod2 is the best nucleator and Tmod3 is the best in sequestering. Although these properties are isoform-dependent, knowledge on how they vary in their strength of interactions to actin is missing.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
