An AFM-based approach for quantification of guest particle deformation during mechano-fusion

Abstract

During the mechano-fusion process for dry particle coating, (hetero)-aggregates are formed consisting of host particles coated by smaller guest particles. During this process, the latter are exposed to intense particle–particle interactions and particle–wall impacts, which lead to deformation of their original shape. These deformations on the nano- and microscale can heavily influence the effective macroscopic properties of the resulting coated particles. We present a method for quantification of shape deformation based on measurements acquired by atomic force microscopy and apply it to guest particles during mechano-fusion. The 3D shape of guest particles is reconstructed by means of an ellipsoidal fit. Using these reconstructed shapes, we quantify the degree of deformation by comparing the aspect ratios of the ellipsoidal fits before and after mechano-fusion. Such a quantification enhances the understanding of how process-related parameters influence geometric descriptors of involved particles, which in turn impacts overall macroscopic properties of the material.