Abstract
Cellular immuodeficiencies other than those associated with human immunodeficiency virus (HIV) are rare, and they usually arise in early childhood (eg, severe combined immune deficiency). Only idiopathic CD4+ lymphopenia has been well-defined to develop in adulthood. Case reports have reported adult-onset T-cell deficiency associated with impaired CD2 expression, and a subtype of common variable immunodeficiency with severe T-cell defect. Here we present an adult with recurrent herpes zoster infection found to have CD4, CD8 T-cell and NK cell deficiency.
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