Abstract
Sirs: The pathophysiology of cyclic vomiting syndrome (CVS) has not yet been established, and treatment for CVS remains unsatisfactory [1, 2]. We herein report an adult case of CVS associated with vascular headache and consciousness disturbance. Valproic acid had a completely protective effect against the vomiting attacks in this patient. The efficacy of an anticonvulsant for CVS thus supported the existence of a nosological link between CVS, migraine, and epilepsy. A 48-year-old woman, with several attacks of vomiting during one hour, was admitted to our hospital seeking treatment for this symptom on December 10, 2005. Nausea and vomiting developed suddenly on the evening of December 9. Her symptoms included fever, headache and palpitations, but no vertigo or abdominal pain. The attack did not subside until the next day, and she visited to her family doctor and then was transferred to our hospital. Her first attack had appeared in August LETTER TO THE EDITORS
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