An administration on artificial skin for burning patient skin recovery through tissue engineering

Abstract

Background: Artificial skin has been tried to implement on subject which is damaged by burn effect.In this research i tried with Silk fibroin as a block biopolymer and which is very high biodegradability and more flexible for cell culture as being a part of human body.With this artificial skin of SF/Chitosan will help to produce more pores of tissue engineering which will create a good implantation system.Skin is the longest and most important organ of human body.Artificial skin is a collagen scaffold that causes skin regeneration in animals such as humans. The innovative biomaterial silk consists of this collagen.I also tried to introduce collagen consisting of silk nanofibers for human body linked to burning patients impacted areas via tissue engineering administration.Body comprises of three layers.They are sometimes called the hypodermis, epidermis, dermis and the fat layer. Purpose: An exploration to implement human compatible artificial skin for burned body. Materials and methods: At first turned silk fibroin through degumming process as a block biopolymer and then check oxygen permeability with silk fibroin and chitosan combination.Check mechanical properties and this total experiment done through tissue engineering and cell culture. Tissue-built skin substitutes may offer a viable helpful choice for the treatment of patients with skin harms. Results: Implementable long term sustainability and high biodegradability artificial skin through cell culture. Conclusion: In this research, artificial skin has been developed with chitosan/SF layer based with complete block biopolymer and i got a significant result which will be compatible for human original skin with high oxygen and water permeability with cell culture and it is effective and result oriented for burning patient skin recovery and accidental case in the replacement of skin. Discussion: Artificial skin is a collagen scaffold that induces regeneration of skin in mammals such as humans.The novel biomaterial silk consists of this collagen.In this research work,we tried to implement collagen consisting silk nanofibers for artificial skin for human body related to burning patients affected areas through tissue engineering administration.