Abstract
A non-fluorescent coumarin-hydrazone conjugate probe was transformed into a strongly fluorescent pyrazolyl coumarin through a thiol-mediated cyclization reaction with F/F0 50. Interestingly, the probe was initially expressed at the cellular cytoplasm but translocated into the membrane regions of cells upon reaction with cellular enriched glutathione, which allowed us to obtain clear membrane imaging in the living cells.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.