Abstract
The favourable early outcome for this patient indicates that a surgical approach is effective for conditions in which severe hypertriglyceridaemia is present. The patient’s syndrome is linked to a high risk of early atherosclerotic cardiovascular disease. Another important consequence of the operation was the reversibility of insulin-resistant diabetes mellitus. It seems likely that insulin resistance observed in this case was due to the presence of high plasma FFA concentrations involved in Randle’s cycle. Insulin resistance proved to be reversible after the operation, which allowed a decrease of triglyceride and FFA plasma concentrations with normal oral glucose absorption. We believe that further evaluation of the proposed approach to the treatment of severe chylomicronaemia is warranted.
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