Abstract
There has been increased interest recently in the concept of dermatomyositis (DM) skin disease occurring for unusually long periods (<6 months) without the development of muscle weakness (i.e., amyopathic DM (syn. DM sine myositis)). This interest has been heightened by the realization that adult-onset clinically amyopathic DM (CADM) and classic DM patients might have similar levels of risk for systemic complications such as interstitial lung disease and internal malignancy. Contrastingly, in juvenile-onset CADM, patients might have a significantly lower risk of the complications of severe calcinosis and cutaneous vasculitis compared with those with juvenile-onset classical DM. This chapter will provide an overview of the diagnostic criteria for CADM, a comparison of the clinical and laboratory features of CADM and classical DM, and a discussion of management issues of DM skin disease including topical and systemic therapy.
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