Abstract
Abstract. Cereals, legumes and oilseeds are characterized by a high protein value and for their potential to prevent cardiovascular diseases. This potential is attributed in part, to the presence of antioxidants and antihypertensive peptides. This study aimed to formulate and develop a drink based on walnut, oat, sesame seeds and soybean to evaluate in vitro its antihypertensive an antioxidant capacity. The beverage was formulated by the method of protein digestibility–corrected amino acid score. Subsequently, the total protein was extracted and hydrolyzed with trypsin. The hydrolysates were analyzed by 2D-PAGE and LC-MS/MS for the identification of bioactive peptides. The antihypertensive capacity was determined by the ACE-1 (Angiotensin converting enzyme) inhibition assay (using captopril as a control) and the antioxidant activity by the methods ORAC and DPPH. This beverage has a 100% protein quality; its protein content covers 48% of the RDA (Recommended Daily Intake). There was presence of antihypertensive (34.34%) and antioxidant (23.34%) peptides. It was observed that 600 μg/mL of hydrolysates inhibited 85% of the activity of ACE-1, while 500 μg/mL of the control inhibited 89.29%, showing significant difference (p
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
