Amphiphilic N-oxyethylimidazolium calixarenes: Synthesis, micellar solubilization and molecular recognition of Adenine-containing nucleotides

Abstract

For the first time amphiphilic calix[4]arenes bearing oxyethyl-imidazolium polar headgroups on one side and alkyl fragments on another side of the macrocyclic platform were synthesized. Critical aggregation concentration (CAC) value was estimated using two methods: (a) pyrene fluorescent probe; (b) fluorescein probe based on both its fluorescent and absorbance properties in micellar solution. All plots were adequately described by a sigmoidal Boltzmann type function. A comparative analysis of the CACs were detected by using two types of dyes was held. The system calixarene - fluorescein was found to different change the absorbance and colorimetric response toward various adenosines phosphates.